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Epidemiology
Ehrlichiosis is a nationally notifiable diseases in the United States. There have been cases reported in every month of the year, but most cases are reported during April-September. These months are also the peak months for tick activity in the United States.

From 2008-2012, the average yearly incidence of ehrlichiosis was 3.2 cases per million persons. This is more than twice the estimated incidence for the years 2000-2007. The incidence rate increases with age, with the ages of 60-69 years being the highest age-specific years.Children of less than 10 years and adults aged 70 years and older have the highest case-fatality rates. There is a documented higher risk of death among persons who are immunosuppressed.