User:Sweetdreams326/New sandbox

Major hormones influencing bone growth and morphology include growth hormone (which acts primarily via inducing IGF-1 production), androgens such as testosterone and dihydrotestosterone, and estrogens such as estradiol.[3][4] GH/IGF-1 are responsible for increasing overall body size, longitudinal bone size, and height, especially during puberty.[3][4] Estrogens cause the hips to widen and become rounded during puberty in females, while androgens cause the shoulders to broaden in males.[5][6][7] According to menoPAUSE, a blog from University of Rochester, estrogen causes females to have their fat distributed in their breasts, thighs, and along their pelvic area, implying that the fat can be used as an energy source for future pregnancies. For men, androgens (such as testosterone) increases male's muscle-to-fat ratio. Estrogens mediate epiphyseal closure in both males and females.[3][4] Other hormones implicated in control of bone growth include thyroid hormone, parathyroid hormone,[8] calcitonin,[9] glucocorticoids such as cortisol, and vitamin D (calcitriol).[4]

Bone Growth Factor on Possible Treatment of Osteoporosis Osteoporosis is a bone disease where bone mass is less than the average and can increase fractures. Some causes that lead to osteoporosis is how old you are, and decreasing amount of estrogen, which is why it mainly occurs in older women (however it can also impact men as well). During a recent study performed at Children's Medical Center Research Institute at UT Southwestern, Bone Growth Factor Osteolectin (Clec11a) has also shown regenerative properties. Ovaries were removed from mice to simulate osteoporosis of post menopausal women. Results were based on daily injections of Osteolectin to determine the effects. This research showed an increase in bone volume of mice with bone loss after their ovaries were removed

To be more specific, in order to help people with osteoporosis, medication is used along with treating bone fractures. Clec11a is a glycoprotein that bone marrow expresses which Elifesciences states.