User:Tahreemasghar/Minigastrin

Peptide Receptor Radionuclide Therapy (PRRT)

A radioactively labeled analogue of minigastrin, PP-F11, conjugated with NOTA, DOTA, or NODAGA was studied to view the effects they have on peptide receptor radionuclide therapy (PRRT) and cancer cell tracing.

Increasing Tumor Uptake

The inhibition of rapamycin complex 1 was discovered to improve the tumor uptake of radioactively labeled minigastrin. In a study conducted in 2021, treatment of A431/CCKBR tumor cells were assessed with DOTA-PP-F11N.