User:Tgirschick/OpenTox

Opentox is a community-based integrating predictive toxicology framework, supported by the EU's FP7 research program, which is taking an Open Source approach to core platform components, an Open Standard's approach to standards including interfaces and ontologies, and a collaborative approach to advancing interoperable development supporting integration of multiple components and licenses into platform-based applications.

Description of Project
The goal of the OpenTox project is to develop a predictive toxicology framework, that provides a unified access to toxicological data, (Q)SAR models and toxicological information.

The OpenTox framework will provide tools for the integration of data from various sources (public and confidential), for the generation and validation of (Q)SAR models for toxic effects, libraries for the development and seamless integration of new (Q)SAR algorithms, and scientifically sound validation routines. OpenTox will attract users from a variety of research areas:
 * Toxicological and chemical experts (e.g. risk assessors, drug designers, researchers)
 * (Q)SAR model developers and algorithm developers
 * Non-(Q)SAR specialists requiring access to Predictive Toxicology models and data

The OpenTox project will move beyond existing attempts to solve individual research issues within this area, by providing a flexible, extensible, and user friendly framework that integrates existing solutions as well as providing easy access to new developments.

Project Partners
Douglas Connect, In Silico Toxicology, Ideaconsult, Istituto Superiore di Sanita', Technical University of Munich, Albert Ludwigs University Freiburg, National Technical University of Athens, David Gallagher, Institute of Biomedical Chemistry of the Russian Academy of Medical Sciences, Seascape Learning and the Fraunhofer Institute for Toxicology & Experimental Medicine

Advisory Board
European Center for the Validation of Alternative Methods, European Chemicals Bureau, U.S Environmental Protection Agency, U.S. Food & Drug Administration, Nestle, Roche, AstraZeneca, LHASA, University North Carolina, EC Environment Directorate General, Organisation for Economic Co-operation & Development, CADASTER and Bayer Healthcare