User:Tnguyen2791/sandbox

Overview
ZNF691 and ZNF691 are a human gene and its protein product, respectively. The official symbol (ZNF691, italic for the gene, nonitalic for the protein) and the official name (zinc finger protein 691) are maintained by the HGNC. Orthologs, styled Zfp691 and Zfp691, are commonly seen more frequent in Mus musculus, while other mammal orthologs retain the term ZNF691.[2] ZNF691 based on ZNF691’s expression profile, it is suspected to be a housekeeping gene [Cite]. This comes from its initially appearance in Scheibe et al.’s research where it is seen to have regulatory control over TERRA expression. ZNF691 is normally expressed in… They are involved in… and add [Clinical relevance research] ZNF691 contains [these domains].

ZNF691 and ZNF691 is the gene and the protein that is expressed, respectively. It is also known as Zinc Finger Protein 691 and ZFP691.

Discovery
ZNF691 was initially found in an applied quantitative mass spectrometry (MS)-based proteomics to identify proteins interacting with telomeric repeat-containing RNA (TERRA). In a knockdown analysis, it is seen to decrease the TERRA/Actin expression levels in HeLa cells.

Locus and Isoforms(cytogenetic/base coordinates, neighborhood)
The human ZNF691 gene is located on the long (p) arm of chromosome 1 at region 34 band 2, from base pair 43,312,244 to base pair 43,318,148 (Build GRCh37/hg19) [cite]. ZNF691 orthologs[2] have been identified in most mammals for which complete genome data are available, to include blank, blank, blank, and blank. ——> Make a chromosome 1 Picture

ZNF691 has three verified isoforms, all due to alternative splicing. [Cite]

Common aliases (if not in ToII)
ZNF691 is synonymous to Zfp691, and both are terms for zinc finger protein 691.

Homology / Evolution
[Add the tree of life and possibly a graph of its mutations throughout time with the species it is found in].

Paralogs
ZNF205 is reported to be the paralog of ZNF691 [Cite].

Orthologs
The list of orthologs are seen to be… [Cite]

Distant homologs
[The Fly?]