User:TransfusionDoctor/Pathogen reduced blood components

= Pathogen-reduced blood components = Blood for transfusion is collected from donors and then processed and stored as different types of blood components (whole blood, red cells, platelets and plasma).

There are risks associated with transfusions, including transfusion-transmitted infections.

A number of methods are used to minimise this risk, and one method is pathogen reduction.

Pathogen reduction is a manufacturing process to reduce the number of infecting organisms in a blood component.

There are several types of pathogen reduction technology, those that can be used for cellular blood components and those that can be used for cell free blood components.

Methods of pathogen reduction for cellular blood components Methods of pathogen reduction for single unit plasma (cell free) blood components Methods of pathogen reduction for pooled plasma components
 * riboflavin (vitamin B2) and UV light (Pathogen reduction using riboflavin and UV light)
 * synthetic psoralen (amotosalen HCl) and UV light
 * UV C light
 * Methylene blue and UV light
 * psoralen and UV light
 * riboflavin and UV light
 * solvent detergent plasma

Medical uses
Pathogen reduced blood components are used routinely in several high income countries around the world. They reduce the amount of certain bacteria, viruses, and parasites within blood components.

Manufacturing
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