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Amsterdam Scientific Instruments
Amsterdam Scientific Instruments manufactures detection systems for X-ray photons, electrons and particles such as ions, neutrons or alpha-particles based on the Medipix technology, developed at CERN. The company was founded in 2013 as a spin-off from Nikhef in Amsterdam and resides currently in the Amsterdam Science Park, in the southeast of Amsterdam, The Netherlands.

Technology
Amsterdam Scientific Instruments manufactures detectors for different applications, such as transmission electron microscopy, X-ray crystallography or velocity mass imaging. The fundamental components of the detectors are:
 * Sensor: usually a monolithic semiconductor from Si, CdTe or GaAs with bump-bonds on the backside. The sensor can be coupled with a photomultiplier or multi-channel-plate.
 * ASIC: pixelated readout microelectronics, manufactured by the Medipix consortium
 * Readout electronics: based on FPGA architecture, provides a raw data stream for further analysis
 * Housing to connect the detector to other instruments, e.g. synchrotron beamlines, transmission electron microscopes

The choice of sensor material depends on the nature of the detected particles and their energy. The aim is to absorb the entire energy of the particle within the detector material to accurately determine the energy and position