User:Ullanki ganesh/Evaluate an Article

Which article are you evaluating?
Toxication

Why you have chosen this article to evaluate?
Today, I am going to explain about TOXICATION .This concept attracted me a lot.

I secured this link from wikipedia .TOXICATION (biochemistry)-the metabolism of drugs and it will produce a toxic METABOLITE .Basically, there are three types of toxic entities. They are from CHEMICAL, BIOLOGICAL ,PHYSICAL.

TOXICATION is a concept obtained from BIOCHEMISTRY .Sometimes we consider  Toxication as poisoning and sometimes TOXICATION is also called PHARMACOLOGY. PHARMACOLOGY tells about a metabolism where the drug or chemical is more toxic.

TOXICATION of a chemical compound is more hazardous or harmful for living organisms. In studies investigation in an intense toxication of different animals .Specific diseases RBC,HGB,HCT in the fluorotic cattle and calves.

SO THESE ARE THE CONCERNS WHY I CHALLENGED MYSELF TO DO THIS ARTICLE FOR EVALUATE.

Evaluate the article.
The goal of toxication and testing is to determine the effects of a particular drug  and which have their own  defined biological systems in their unique way .TOXICATION is a concept where the amount of  substance needs to be poisonous.

TOXICATION is a state or relative degree of being poisonous or the toxicity of some agents .Sometimes toxication is also calculated in soil and water or in any substances .Parent molecules are referred to as non toxic .TOXICATION IS GENERALLY UN DESIRABLE.

INTOXICATION THERE ARE DIFFERENT CONTENTS. THEY ARE EXPLAINED IN BELOW.

THEY ARE :-

TOXICATION BY ENZYMATIC METABOLISM here is classified into three different concepts .they are

CYP450 enzymes:-Drug metabolism are bioactive pathways. Here, CYP450 ENZYMES has their own subfamily like CYP2D6 and CYP3A. This enzyme is toxic to the liver.

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OTHER OXIDOREDUCTASES:-This enzymes are involved in the transfer of electrons.

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OTHER EXAMPLES:-NICOTINE into the nitrosated carcinogen NNK (4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE).

MOREOVER COMBINATION OF ARSENIC IN DRINKING WATER IS TOXIC.