User:Vnvmsnc56/Beta-Neoendorphin

β-neoendorphins (β-NEP) have the capability to stimulate wound healing by accelerating keratinocyte migration. This is achieved by β-NEP's activation of mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinases 1 and 2 (ERK 1 and ERK 2); along with the upregulation of matrix metalloproteinase 2 and 9 (MMP-2 AND MMP-9). Wound healing by β-NEP results in migration without consequences on proliferation in human keratinocytes.