User:Vrwclemson/Choose an Article

Article Selection
Please list articles that you're considering for your Wikipedia assignment below. Begin to critique these articles and find relevant sources.

Option 1

 * Article title
 * Endorphins


 * Article Evaluation
 * The introduction is a good summary of all of the sections and the article remains neutral. The Types section needs expansion. The introduction states that the class of endorphins is pharmacologically classified but the section only classifies them based on size and gives the peptide sequence in a table. Both the synthesis and mechanism of action sections need more sources. The functions section mentions needs more medical references that follow MEDRS guidelines as many of them rely on primary sources. The Talk page highlights similar issues regarding sources and also highlights that some text relies heavily on medical jargon—which is very confusing to read. Editors have also talked about poor sourcing for claims about endorphins as they relate to sex, “runner’s high” and chocolate.


 * Sources
 * Sprouse-Blum, A. S., Smith, G., Sugai, D., & Parsa, F. D. (2010). Understanding endorphins and their importance in pain management. Hawaii medical journal, 69(3), 70–71 PMID#20397507
 * Schwartz, J. C., & Roques, B. P. (1980). Opioid peptides as intercellular messengers.  Biomedicine / [publiee pour l'A.A.I.C.I.G. , 32(4), 169–175.] PMID#6110445
 * Chaudhry SR, Gossman W. Biochemistry, Endorphin. [Updated 2020 Aug 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020. ]

Option 2

 * Article title
 * Acetylcholine receptor


 * Article Evaluation
 * The introduction could be expanded to better summarize the article and give more basic information on the ACh receptor. There is no sourcing within the Classification section for the between the two types of ACh receptors. This section is co-morbid with the Receptor Types section and could be either combined or deleted. Some sentences do not seem reliable like: “Molecular biology has shown hat the nicotinic and muscarinic receptors belong to distinct protein super families” which could be revised to sound more reliable. The phrasing of the entire Receptor Types section could be revised to be understood more clearly as well. Drugs under the Pharmacology section do not have a page: AChEi, DMPP, Dextromethophan, Ipatriopium, & Methoctramin. The role in health and disease section could also use more MEDRS sourcing as well as more souring in general. The Talk Page specifically highlights similar concerns over the claims made related to health. Other concerns were raised over the pharamacology table legend and pictures meeting correct criteria.


 * Sources
 * Brain nicotinic acetylcholine receptors: native subtypes and their relevance https://doi.org/10.1016/j.tips.2006.07.004
 * A late-onset congenital myasthenic syndrome due to a heterozygous DOK7 mutation https://doi.org/10.1016/j.nmd.2020.02.009

Option 3

 * Article title
 * Eukaryotic translation


 * Article Evaluation
 * The introduction and organization of the article is simple and easy to read. The information regarding eukaryotic elongation and termination could be expanded and fitted with images to match that of the section on initiation. The cap-dependent section is dense making it difficult to read—it could use reformatting. The information overall is unbiased and comes from multiple good sources, however, an explanation of the elementary concept of eukaryotic translation could be based on textbook information rather than articles that describe it as a part of their introduction (as in the Elongation section). The photos used in Initiation could have a better legend. The Talk page does not have any editors except for the original creator of the article. Additional information on initiation factors and its relation to cancer could be added—linked in the sources below.


 * Sources
 * Jackson, R. J., Hellen, C. U., & Pestova, T. V. (2010). The mechanism of eukaryotic translation initiation and principles of its regulation. Nature reviews. Molecular cell biology, 11(2), 113–127. https://doi.org/10.1038/nrm2838 PMID# 20094052
 * Ali, M. U., Ur Rahman, M. S., Jia, Z., & Jiang, C. (2017). Eukaryotic translation initiation factors and cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39(6), 1010428317709805. https://doi.org/10.1177/1010428317709805 PMID# 28653885