User:Warfieldian/Neti Pot Notes

Research articles
Fluid residuals and drug exposure in nasal irrigation. Harvey RJ, Debnath N, Srubiski A, Bleier B, Schlosser RJ.

1.	Rabago D, Zgierska A, Mundt M, Barrett B, Bobula J, Maberry R. Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: A randomized controlled trial. Journal of Family Practice. 2002;51(12):1049-1055.

2.	Rabago D, Pasic T, Zgierska A, Barrett B, Mundt M, Maberry R. The efficacy of hypertonic saline nasal irrigation for chronic sinonasal symptoms. Otolaryngol Head Neck Surg. 2005;133:3-8.

3.	Rabago D, Barrett B, Marchand L, Maberry R, Mundt M. Qualitative aspects of nasal irrigation use by patients with chronic sinus disease in a multi-method study. Annals of Family Medicine. 2006;4:295-301.

4.	Rabago D, Guerard E, Bukstein D. Nasal irrigation for chronic sinus symptoms in patients with allergic rhinitis, asthma and nasal polyposis: a hypothesis generating study. Wisconsin Medical Journal. 2008;107:69-75.

5.	Rabago D, Bamber A, Peppard P: The awareness and use of nasal irrigation among family medicine physicians in Wisconsin; Wisconsin Medical Journal; In Press, 2009

6. Harvey R, Hannan S, Badia L, Scadding G. Nasal saline for the symptoms of chronic rhinosinusitis. Cochrane Database Syst Rev. July 18 2007;3(CD006394)

Possibly harmful effects
"The study, presented this week at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Meeting in Miami, followed 68 people who used nasal saline irrigation for 12 months and then discontinued use for another 12 months.

The results showed that the number of cases of sinusitis decreased by 62.5% during the discontinuation phase. Researchers also compared the rates of sinusitis among those who stopped using nasal saline irrigation and another group of 24 adults who used daily nasal saline irrigation for 12 months. Again, they found sinusitis among daily users was significantly higher (50%) than among nonusers.

Researchers say nasal mucus acts as a first line of defense against infections, and long-term nasal saline irrigation may interfere with this natural immune function.

Although use of a neti pot for nasal saline irrigation may temporarily improve sinus infection symptoms, they say "its daily long-term use may result in an increased frequency of acute [sinusitis] by potentially depleting the nose of its immune blanket of mucus," write researcher Talal M. Nzouli, MD, of Washington, D.C., and colleagues in their study." Source: http://www.webmd.com/allergies/news/20091109/long-term-neti-pot-use-may-backfire  Journal: American College of Allergy, Asthma and Immunology (ACAAI) Annual Meeting, Miami Beach, Fla., Nov. 5-10, 2009.