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= Sulfolobus sulfataricus:biotechnologie =

Untapping the resource Sulfolobus
Today, in many fields of application, we are interested in using Sulfolobus sulfataricus as a source of thermal stability enzymes for research and diagnostics, as well as in the food, textile and cleanning industries, and the pulp and paper industry.Furthermore, this enzyme is overloaded due to its catalytic diversity, high pH and temperature stability, increased to organic solvents and resistance to proteolysis.

At present, tetraester lipids, membrane vesicles with antimicrobial properties, trehalose components, and new β-galactooligosaccharides are coming increasingly important.

β-galactosidase
The thermostable enzyme β-galactosidase isolated from the extreme thermophile archaebacterial Sulfolobus solfataricus, strain MT-4.

This enzyme utilized on many industrial process of lactose containing fluids by purifying and characterizing for their physicochemical properties.

Proteases
The industry are interested in stable proteases as well as in many different sulfolobus proteases that have been studied.

An active aminopeptidase associated with the chaperonin of Solfobulus solfataricus MT4 was described.

Sommaruga et al.(2014) also improved the stability and reaction yield of a well-characterized carboxypeptidase from S.solfataricus MT4 by magnetic nanoparticles immobilizing the enzyme.

Esterases/Lipases
A new thermostable extracellular lipolytic enzyme serine arylesterase which is originally discovered for their large action in the hydrolysis of organophosphates from the thermoacidophilic archaeon Sulfolobus solfataricus P1.

Chaperonins
In reaction to temperature shock (50.4°C) in E.Coli cells, a tiny warm stun protein (S.so-HSP20) from S.solfataricus P2 has been effectively used to imrove tolerance.

In view of the fact that chaperonin Ssocpn (920 kDa), which includes ATP, K+ and Mg2 + but has not produced any addtional proteins in S.solfataricus to supply collapsed and dynamic proteins from denatured materials ,it was stored on an ultrafiltration cell, while the renatured substrates were moving through the film.

Liposomes
Because of its tetraether lipid material, the membrane of extreme thermophilic Archaea is unique in its composition. Archaea lipids are a promising source of liposomes with exceptional stability of temperature and pH and tightness against leakage of solute. Such archaeosomes are possible instruments for the delivery of medicines, vaccines, and genes.