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The Olson Lab at the University of California, Davis studies psychoplastogens to research potential therapeutic applications such as treating addiction and depression.The group is combined of researchers of different expertise such as chemistry and neuroscience. Their work involving chemistry includes total synthesis of psychoplastogens and related analogs, optimizing the safety by studying relationships of the activity of certain psychoplastogen structures, and developing molecular strategies to help research neurobiology.Their work involving neuroscience involves researching neural plasticity, the mechanisms on how psychoplastogens influence behavior and could be used for treating disorders. The use of psychoplastogens as medicine to potentially cure mental illnesses is emphasized in this publication by Olson. His work on optimizing experimental conditions for synthesizing certain psychoplastogens have opened a big door for the future psychedelic science. For example, Olson researched the exposure of DMT (and various structures that have the same structural core) to DCM (a common solvent used during the workup process but could lead to unwanted byproducts) in various experimental conditions. The significance was to optimize conditions to minimize the formation of the unwanted quaternary ammonium salt byproduct and also minimize any possible degradation. This has applications in allowing pharmaceuticals with the DMT core structural core to be obtained with high yield and purities. Olson has many other research papers that focus on synthetic methods that allow for high yields. For example, his research on using C-H amination allowed for access to 1,2-diamine derivations, which are present in many biologically active structures. This synthetic route involved a minimal number of steps suggesting a convenient method to access these structures seeing that the starting materials are simple alcohols. Olson developed a synthetic route to make Pactamycin, an aminocyclitol natural product. This involved reactions that formed oxidative C-N bonds, and used methods of alkene amination. The Olson group's research work has been featured in many reputable science medias such as Nature, Science, and Time. This has gave more spotlight and credibility for psychoplastogens to be more clinically researched neurotherapeutic applications. Olson has also spoke on many notable news outlets such as Pharmacy Times, NPR, and the BBC. Olson's research and interests in the total synthesis and medicinal chemistry of psychedelics works alongside with the interests of UC Davis' Institute for Psychedelics and Neurotherapeutics. The unique aspect of their laboratory that involves the combination of many different sciences has allowed their research to be very detailed in all aspects: chemistry, biology, neuroscience, and psychology. David Olson's research that helped the formation of Delix Therapeutics, which he is a co-founder of, has allowed for the development and research of many neuroplastogens. The aim of this company is to push forward more scientific research to be done on neuroplastogens and use these compounds for potential therapeutic applications that could treat neurological conditions. As mentioned, David Olson's research on psychoplastogens is not only in an academia space, but it extends out to other research platforms such as Delix Therapeutics. His research emphasizes many different areas of science and has allowed to psychedelics to be a considered as a medicine for treating various disorders and illnesses.