User:WillowW/FAC notes

Antioxidant
rewrite lead, more lively, logical flow

antioxidant: prevent oxidation from happening in the first place, NOT to repair the damage after it's done

more chemistry of oxygen and oxidation singlet oxygen and UV light principal attack on normally unreactive hydrocarbons found in lipids, oils, waxes electron-hungry feeding on the electron-rich; extremely high reactivity of radicals, random uncntrolled creation of new chemicals, detox useful to mention redox potential of selenium vs. sulfur? probably not loss of elasticity in rubber, deactivation of gasoline

oxygen is not necessarily involved; any free radical or redox-active species

"deactivate free radicals" evocative phrasing; also "mopping up", "neutralizing" free radicals

carcinogenic N-nitroso compounds that result from nitrites and nitrates; nitrosamines damage DNA

hypoxia vs. oxygen starvation more on biological oxidation; peroxisome perhaps?

Free radicals occur naturally, and also in response to environmental stimuli

List typical oxidizing agents that antoxidants work against: singlet oxygen, superoxide, hydroxyl radicals, peroxyl radicals, peroxynitrite

define "chain-breaking" antioxidants such as lycopene

oxidative stress from smoking, sunburn,...

Most antioxidants in North American diet comes from coffee :D oxidation can be catalyzed by metal ions; can chelators be considered as "antioxidants"?

mention discoloration along with rancidity; browning of apples a common example antioxidation in beers; long-term preservation of cosmetics

strengthen industrial applications, although don't undermine health emphasis; chance to do good wiki-link to E numbers (E300-E321) add abbreviations, esp. BHA and BHT, vitamin E analogs; familiar from cereal boxes! :) propyl gallate, octyl gallate, dodecylgallate; mention thermal instability

plant metabolism engineering to increase tocopherols, improve rapeseed oil storage time

allergies to antioxidants

polyphenols, flavonoids, carotenoids - other isoprenoids? Do they work like sacrificial lambs, decoy targets? Carcinogenesis related to hydrophobicity; chimney-sweep effect

trypanothione ;) oxidative stress and connection to fasting, need to find that again

is there any chance that, under oxidative stress, the cytosol would allow for forming unwanted disulfide bonds? Probably not, but check?