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Nihal Altan-Bonnet is a cell biologist who currently works in the NIH as an Earl Stadtman Investigator in the Laboratory of Host-Pathogen Dynamics.

Biography
Nihal Altan-Bonnet became interested in biology and research at a young age when her mother was diagnosed with breast cancer. This experience fueled her to study biology as she wanted to learn more about cancer. She initially became interested in studying cell motility and metastasis. She earned her bachelor’s degree in biology and chemistry at Hunter College in 1992. In 1998, she earned a Ph.D. in cell biology from The Rockefeller University. She specialized in breast cancer research while completing her thesis for her PhD. After earning her degrees, Bonnet worked with Dr. Jennifer Lippincott-Schwartz on her Postdoctoral fellowship from 1999-2005 at the National Institute of Child Health and Development. In 2006, she joined the Rutgers University-Newark faculty in the department of biological sciences, focusing her research on infectious pathogens and viruses. Recently, in 2013, she began working in the Laboratory of Host-Pathogen Dynamics at the NIH as an Earl Stadtman Investigator. Bonnet’s research interests include infectious pathogens and viruses, virus-cell interactions, replication process of viruses, the viral life cycle, etc.

Awards and Achievements
In 2011, Bonnet received the Young Investigator Award from the Theobald Smith Society of the American Society for Microbiology. Bonnet received the Presidential Early Career Award for Scientists and Engineers (PECASE) in 2012. She received this award for pursuing innovative research on membrane blueprints for viral replication. Through her research, Bonnet found that many different viruses have the same membrane blueprint for replication.

Bonnet has many recognizable publications, some featured ones include:

Intercellular Transmission of Viral Populations with Vesicles. Altan-Bonnet N, Chen YH J Virol 2015 Dec 01;89(24):12242-4.

Nihal Altan-Bonnet: Tracking viruses that hijack membranes. Altan-Bonnet N, Powell K J Cell Biol 2015 Sep 28;210(7):1038-9.

Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses. Chen YH, Du W, Hagemeijer MC, Takvorian PM, Pau C, Cali A, Brantner CA, Stempinski ES, Connelly PS, Ma HC, Jiang P, Wimmer E, Altan-Bonnet G, Altan-Bonnet N Cell 2015 Feb 12;160(4):619-30.

Enteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replication. Ilnytska O, Santiana M, Hsu NY, Du WL, Chen YH, Viktorova EG, Belov G, Brinker A, Storch J, Moore C, Dixon JL, Altan-Bonnet N Cell Host Microbe 2013 Sep 11;14(3):281-93.

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Hsu NY, Ilnytska O, Belov G, Santiana M, Chen YH, Takvorian PM, Pau C, van der Schaar H, Kaushik-Basu N, Balla T, Cameron CE, Ehrenfeld E, van Kuppeveld FJ, Altan-Bonnet N Cell 2010 May 28;141(5):799-811.