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Mandalay Bay Events Center

Rock band Journey performed at the arena in December 2000 which was filmed for the Journey 2001 DVD.

It has hosted the Latin Grammy Awards five times. The Latin Grammys were held at the Mandalay Bay Events Center in 2007 and from 2009 to 2013. VH1 held the first two Rock Honors ceremonies in this facility in 2006 and 2007.

It was the host of Yanni's Yanni Live! The Concert Event, in 2006.

The arena hosted Crüe Fest on August 1, 2008.

It played host to 311's biennial 3-11 Day concert on March 11, 2010. The band played four sets with 60 songs total.

The arena hosted the 2010 revival of the Lilith Fair on July 9.

On August 23, 2010 the arena served as the venue for Miss Universe 2010 where at the conclusion of the event Ximena Navarrete of Mexico was crowned as the winner.

January 28, 2011, Ozzy Osbourne performed as part of his tour for his new album Let Me Hear You Scream.

The cast of Glee were there on the first stop on their Glee Live! In Concert! tour on May 21, 2011.

On May 14, 2017 the arena hosted Miss USA 2017 pageant.