User:YQDeng/Rif (GTPase)

Article body
Rif is one way of generating filopodia (rif-induced filopodia) through its interaction with mDia2. Specifically, the interaction between rif and mDia2 involves a GTP from Rif reacting with the GTPase binding domain (GBD) of mDia2.

The coexpression of Rif with Rac or Cdc42, other GTPases that also participate in regulating cell structure and morphology, can give rise to new filopodial structures that differ from the filopodia arrangements stimulated by each of these GTPases separately.