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Henrik Bruus (born 5 April 1963) is a Danish physicist and educator, working primarily in the area of microfluidics.

Bruus is a graduate of the University of Copenhagen and recieved his M.A. in 1986, and his Ph.D. in 1990. He did his post-doctoral research at Yale University and has been a professor at the Technical University of Denmark since 2005. He has headed the department of biophysics and fluid mechanics research since 2012. He has been a visiting professor at Harvard University, Massachusetts Institute of Technology and Princeton University among others. In 2011, he was named a Fellow of the American Physical Society. He has written two graduate textbooks, one in condensed matter physics and one in microfluidics.