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Methanol poisoning[edit]
Acute alcohol poisoning has high morbidity and mortality and needs to be considered seriously and instantly managed. Delay in treatment may cause complications, permanent damage, or death.

Methanol is a sedative for central nervous system (CNS) which is potentially toxic. Once people ingest excessive methanol, it will lead to methanol poisoning and severe consequences for health. Because it produces poisonous metabolites, it has many adverse effects on vision, and central nervous system, and the liver. Toxic metabolites accumulate more and have a more significant impact on health and sometimes poison to death. According to the autopsy, methanol is stored in body fluids such as cerebrospinal fluid and bile.These fluids are in organs of the brain, spleen, and lungs. Therefore, these organs are vulnerable to excessive ingestion of methanol.

Short-term health effects of methanol poisining[edit]
The short-term manifestations of methanol poisoning begin within 0.5 to 4 hours after ingestion, increased heart rate, and the possibility of heart failure, including typical symptoms of gastrointestinal diseases such as vomiting, diarrhea, nausea or abdominal pain, and CNS inhibition (confusion and sleepiness). The following are the physical symptoms of mild central nervous system poisoning. Patients manifest different symptoms such as headache, dizziness, blurred consciousness, balance disorder, convulsions, stiffness, coma-induced apathy, and worsening pronunciation and memory impairment. Severe poisoning manifests mainly in CNS. In the brain, methanol can cause diffuse edema, necrosis white and grey matter, atrophy, cerebral and intraventricular haemorrhage, optic haemorrhages, nerve lesions, and convulsions that may occur after edema of the brain. In severe cases, seizures of the brain can cause a coma.

Depending on the absorbed dose, decompensated metabolic acidosis occurs after a latent period of 6 to 24 hours. It can also result in Visual disturbances such as blurred vision, enlarged pupils. With photophobia, diplopia, early or late blindness, and less commonly, nystagmus.