User:Yousra claudia

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Teg10 Trans-encoded antisense RNA

The RNA regulators, named small RNAs (sRNAs) in prokaryotic organisms, constitute a heterogeneous group of molecules that act by various mechanisms to modulate a wide range of physiological responses. RNAIII, for example, is the largest and best studied sRNA in S. aureus that controls the temporal expression of numerous virulence genes encoding exoproteins and cell wall-associated proteins. Overall, sRNAs can modulate transcription, translation, mRNA stability, DNA maintenance or silencing. Thus, these RNA regulators can play a major role in the complex process of epidemicity and virulence as well as for adjusting to diverse environmental stresses. Various regulatory mechanisms involving sRNA have been reported and include changes in RNA conformation using riboswitches, protein binding, base pairing with mRNAs, and interaction with DNA.