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Charles Safran (born February 3, 1951) is an American-born physician, biomedical informatician, and professor, who is internationally renowned for his work regarding the use of health information technology (HIT) to improve the delivery and quality of healthcare, in particular clinical information systems.

Biography and career
Charles Safran was born on February 3, 1951, in New York, New York, United States. He attended college at Tufts University, where he earned his B.S. in Mathematics and Logic in 1979. He received an M.D. from Tufts University in 1980. He received an honorary A.M. degree from the Harvard University in 2015. Safran's postdoctoral training included an internship and residency in Internal Medicine at the Boston Veterans Administration Medical Center from 1980 to 1983. Safran's diverse professional roles have included early positions as a Programmer and Sponsored Research Staff at MIT's Laboratory for Computer Science. Safran has had a long-standing association with Harvard Medical School, serving in various capacities from an Instructor in Medicine (1983-1987) to his current position as a Professor of Medicine, a role he has held since 2015.

During his career, he has helped to pioneer and deploy large institutional integrated clinical computing systems, ambulatory electronic health records and clinical decision support systems to help clinicians treat patients.

He has held numerous positions at Beth Israel Hospital as a physician and former Chief of the Division of Clinical Informatics. Safran has been influential in shaping medical informatics education and research. He has directed research programs and led clinical computing fellowships. He has also played a crucial role in developing biomedical informatics programs at Harvard Medical School and the development of the national board certification for medical informatics. He has held significant leadership positions outside academia. From 2007-2010, He was a senior scientist at the National Center for Public Health Informatics at Center for Disease Control and Prevention. He was CEO of Clinical Support Technology (1999-2004) where he successfully brought his ideas to a national market. The company’s products and technology were acquired by a major public company. He has over 150 peer-reviewed publications and speaks to national and international audiences.

Awards and honors

 * AMIA Leadership Award, American Medical Informatics Association, 2001
 * AMIA Leadership Award, American Medical Informatics Association, 2006
 * AMIA Leadership Award, American Medical Informatics Association, 2015
 * AMIA Don Eugene Detmer Award for Health Policy Contributions in Informatics, American Medical Informatics Association, 2013
 * Morris F. Collen Award of Excellence, American Medical Informatics Association, 2014