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Diploid-triploid mosaicism
Diploid-triploid mosaicism, also known as diploid-triploid mixploidy is a disease characterized by a chromosomal abnormality in which an individual has some diploid cells (46 chromosomes) and some triploid cells (69 chromosomes). It is called a 'mosaicism' since both diploid and triploid cells exist throughout the body. Homo sapiens have diploid cells, excluding gametes, and any person born with triploid cells (triploidy) often dies in the womb or shortly after birth. People born with diploid-triploid mosaicism have a much greater chance for survival, but do suffer from developmental and physical abnormalities and in severe cases, cognitive defects.

== Symptoms  ==


 * facial feature and body asymmetry
 * low set ears and jaw
 * full or partial webbing between fingers and toes
 * weak muscle development
 * truncal obesity
 * skin pigmentation abnormalities


 * mental retardation
 * other intellectual disabilities occur but depend on severity of the disorder

Diagnosis
The triploid cells are exclusively found in specific tissues rather than throughout the body. Testing the karyotype in blood can't detect the presence of the extra set of chromosomes; however, a skin biopsy, more specifically the fibroblasts, reveal the syndrome. Additional testing of the urinary cells can confer the results of the skin biopsy.

How diploid-triploid mosaicism occurs
The extra set of chromosomes can come from the father or mother. This can occur if the mother has a diploid ovum fertilized by a haploid sperm or if a diploid sperm fertilizes a haploid ovum. When the mother provides the extra set of chromosomes, it is known as digynic triploidy, and diandric triploidy occurs when the father contributes the extra set. It is possible that an additional sperm cell interacts with an embryonic blastomere, thus contributing to the extra set of chromosomes.

Treatment and Prognosis
Diploid-triploid mosaicism is non-hereditary and there are no risk factors associated with the syndrome .Diploid-triploid mosaicism is a genetic disorder so there is no treatment or cure. Physicians treat the symptoms caused by the disorder. Furthermore, the life-expectancy and prognosis depends on the severity of the disorder. Patients have been known to survive well into adulthood, but typically this is highly variable.