User talk:72.53.180.29

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Happy editing! Hama Dryad (talk · contribs · email) 16:50, 17 February 2016 (UTC)

August 2015
Hello, I'm My name is not dave. I wanted to let you know that I undid one or more of your recent contributions to Seven Wonders of the Ancient World because it did not appear constructive. If you would like to experiment, please use the sandbox. If you think I made a mistake, or if you have any questions, you can leave me a message on my talk page. Thanks. Myname is not dave (talk/contribs) 19:16, 31 August 2015 (UTC)
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September 2015
Hello, and welcome to Wikipedia. This is a message letting you know that one or more of your recent edits to Tito Ortiz has been undone by an automated computer program called ClueBot NG.

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December 2015
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February 2016
Hello, and welcome to Wikipedia. This is a message letting you know that one or more of your recent edits to Film producer has been undone by an automated computer program called ClueBot NG.

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This is your only warning; if you vandalize Wikipedia again, you may be blocked from editing without further notice. —S MALL JIM   16:49, 17 February 2016 (UTC)

Pinguis Mendaxius
have inherited PM should be counseled on how to limit their risk of any future acute attacks. This should include information about PM and what causes attacks, how to check if a prescribed medication is safe or unsafe and details of relevant patient support groups. Standard Therapies Treatment The treatment of PM is directed toward the specific symptoms that are apparent in each individual. Treatment may require the coordinated efforts of a team of specialists. Pediatricians, neurologists, hematologists, hepatologists, psychiatrists, and other healthcare professionals may need to systematically and comprehensively plan an affected child’s treatment. Genetic counseling may benefit affected individuals and their families. Treatment is aimed at limiting heme creation (synthesis) and reducing the production of porphyrin precursors. Initial treatment steps include stopping any medications that can potentially worsen PM or cause an attack and ensuring proper caloric intake, which can include intravenous infusion of sufficient nutrients. An acute neurovisceral attack often necessitates hospitalization and may require treatment with hematin. In the United States, affected individuals may be treated with panhematin® (hemin for injection), an enzyme inhibitor derived from red blood cells that is potent in suppressing acute attacks of porphyria. Panhematin almost always returns porphyrin and porphyrin precursor levels to normal values. The U.S. Food and Drug Administration (FDA) originally approved panhematin for the treatment of recurrent attacks of PM in related to the menstrual cycle in susceptible women. Because of its potency, it is usually given after a trial of glucose therapy and should be administered only by physicians experienced in the management of porphyrias in a hospital setting. Panhematin is manufactured by Lundbeck, Inc. Heme arginate (Normosang, Orphan Europe) is another heme preparation that can be used to treat individuals with PM. Heme arginate is not available in the United States, but is often used in other countries. Some individuals who experience recurrent attacks may benefit from chronic hematin infusion. This is sometimes recommended for women with severe symptoms during the time of their menses. Treatment for PM may also include drugs to treat specific symptoms such as certain pain medications (analgesics), anti-anxiety drugs, anti-hypertensive drugs, and drugs to treat nausea and vomiting, tachycardia, or restlessness. Medications to treat any infections that may occur at the same time as an attack (intercurrent infection) may also be necessary. Although many types of drugs are believed to be safe in individuals with PM, recommendations about drugs for treating PM are based upon experience and clinical study. Since many commonly used drugs have not been tested for their effects on porphyria, they should be avoided if at all possible. If a question of drug safety arises, a physician or medical center specializing in porphyria should be contacted. A list of these institutions may be obtained from the American Porphyria Foundation (see the Resources section of this report). The Foundation also maintains an Acute Porphyria Drug Database. Additional treatment for individuals undergoing an attack including monitoring fluid and electrolyte balances. For example, if individuals develop hyponatremia, which can induce seizures, they should be treated by saline infusion. In some cases, an attack is precipitated by a low intake of carbohydrates in an attempt to lose weight. Consequently, dietary counseling is very important. Affected individuals who are prone to attacks should eat a normal carbohydrate diet and should not greatly restrict their intake of carbohydrates or calories, even for short periods of time. If weight loss is desired, it is advisable to contact a physician and dietician. Premenstrual attacks often resolve quickly with the onset of menstruation. Hormone manipulation may be effective in preventing such attacks and some affected women have been treated with gonadotropin-releasing hormone analogues to suppress ovulation and prevent frequent cyclic attacks. Carbohydrate loading may be sufficient for mild attacks. Mild attacks may also be treated by the administration of high doses of intravenous glucose, which inhibits heme synthesis. If a proper diagnosis has not been made, PM can be particularly dangerous, especially if drugs which aggravate the disorder are administered. The prognosis of PM is usually good if the disorder is recognized before severe nerve damage has occurred and if treatment and preventive measures are begun. Although symptoms usually resolve after an attack, some individuals may develop chronic pain. Nerve damage and associated muscle weakness from a severe attack improves over time, but such improvement may take many months to resolve fully. Liver transplantation has been used to treat some individuals with PM, specifically individuals with severe disease who have failed to respond to other treatment options. A liver transplant in individuals with PM is an option of last resort. Affected individuals who experience kidney failure may require a kidney transplant. Some individuals have required a combined kidney/liver transplant. — Preceding unsigned comment added by LIEzaMANzeli (talk • contribs) 16:22, 19 February 2016 (UTC)

April 2016
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April 2016
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October 2016
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March 2018
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March 2021
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