User talk:79.22.244.124

Thyrogastric syndrome
Thyrogastric syndrome defines the association between thyroid disease and chronic gastritis, and it was first described in the 1960s This term was coined also to indicate the presence of thyroid autoantibodies or autoimmune thyroid

disease in patients with pernicious anemia, a late clinical stage of atrofic gastritis. In former studies, the association was assessed serologically. In 1993, Venturi proposed a more

complete investigation of the gastric mucosa and cancer and the thyroid gland, reporting that the thyroid is, embryogenetically and phylogenetically, derived from

primitive gut, and that the thyroid cells, such as primitive gastroenteric cells, during vertebrate evolution, migrated and specialized in uptake of iodide and in

storage and elaboration of iodine compounds. In fact, stomach and thyroid share iodine-concentranting ability and many morphological and functional similarities, such

as cell polarity and apical microvilli, similar organ-specific antigens and also associated autoimmune diseases, secretion of glycoproteins (thyroglobulin and mucin)

and peptide hormones, the digesting and readsorbing ability and, lastly, similar ability to form iodotyrosines by peroxidase activity, where iodide acts as electron

donor in the presence of H2O2. In the following years,

many researchers published studies about this syndrome.

--79.22.244.124 (talk) 20:07, 1 January 2020 (UTC)Venturi Sebastiano, Jan. 1,  2020--79.22.244.124 (talk) 20:07, 1 January 2020 (UTC)