User talk:ADSky/sandbox

Your sandbox looks pretty organized but you could add more infection on the mycosis section, naming few conditions caused by your organism. As per my research Neoscytalidium dimidiatum was responsible for mycetoma in South India. You could take a look at it, it might be an interesting fact. It also cause Stem Canker Disease of Pitaya (Hylocereus undatus and H. polyrhizus) in Taiwan, which you could include too.I found this report of Shoot Blight, Canker, and Gummosis Caused by Neoscytalidium dimidiatum on Citrus in Italy. You could talk about it's geographical distribution.

I also found out how the technique of matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) could be used to identify/isolate Neoscytalidium dimidiatum. May be you could write a little bit on that too.

You could also talk about how it causes onychomycosis and dermatomycosis. I also found another on report a case of pulmonary infection with Neoscytalidium dimidiatum in an immunocompromised patient. However it affects both immunocompetent and immunosuppressed individuals, and it may invade deeper tissues and organs and cause systemic disease. found this info and how animal models were used to study Neoscytalidium dimidiatum in this article : "Cutaneous murine model of infection caused by Neoscytalidium dimidiatum: a preliminary study of an emerging human pathogen."

"Evaluation of antifungal therapy in a neutropenic murine model of Neoscytalidium dimidiatum infection." This article is something which talks about treatment, so I found this interesting too.

As I mentioned before your article looks very nice and organized. Just add a few interesting facts for readers. Good luck! AdibaR (talk) 03:42, 27 October 2016 (UTC)

Comments by Zikynsk
Hi, ADSky!

I have looked through your outline and it is a very good outline that covers the basic categories that our professor asks ☺. Below are a few suggestion that I thought of while reading the outline. They are only my opinion that I cannot be sure I am right. So, if you feel like I am wrong, feel free to not follow them or you can leave a reply underneath for further discussion.

-	When I googled synanamorph, its defintion is when a single fungus produces multiple morphologically distinct anamorphs. If they have different morphologies, why did sctyalidium dimidiatum was considered a synanamorph of Nattrassia mangiferae? You may elaborate more on that in the history section. Besides, you may link this to the taxonomic difficulties seciton when you mentioned that neoscytalidium dimidiatum and neofusicoccum mangiferase are two different species.

-	In the taxonomy section, it is surprising that they have so many different names. I am curious if they are the names of Neoscytalidium dimidiatum in different anamorph and teleomorph stages. Or are they just randomly named by the scientists who discovered them without knowing that they have been previously recorded (because these names are created in years pretty distinct from each other)

-	It is somewhat confusing in the Taxonomic difficulties section. Are the naming events listed in an order of time? You may want to add the year after each naming events and describe how the same fungus can have different results of sequence analysis and molecular anaylsis that leads to the different naming. Also, I would suggest to use only one name of a fungus instead to interchanging between their common names when describing it, such as keeping using the name of “Nattrassia mangiferae” and don’t use “Neofusicoccum mangiferae”.

-	From the same section, I wonder if the sequence and molecular structure of Scttalidium dimidiatum are similar to neoscytalidium dimidiatum’s because they just added a “neo-“ in the front.

-	For the myocsis section, you may want to divide it up into two paragraphs (on the final article) of pathogenicity in plants and pathogenicity in human caused by contaminated plants or soil. Again, is Hendersonula toruloidea the same fungus as Neoscytalidium dimidiatum? If it is, stay with one name. In addition, you can look up the symptoms that this fungus caused in plants. And are there any treatments for Scytalidiosis?

-	Lastly, remember to italize all the fungi names and if a fungi name is repeatedly mention in a paragraph and not in the beginning of a sentence, you may choose to use short form, eg. N. mangiferae.

-	Below are some literature that can provide additional information of your fungus:

1.	https://www.ncbi.nlm.nih.gov/pubmed/25948605 (reported a case of pulmoary infection caused by Neoscytalidium dimidiatum).

2.	https://www.ncbi.nlm.nih.gov/pubmed/26471716 (treatment to onychomycosis)

3.	http://link.springer.com/article/10.1007/s13314-015-0166-1 (a fruit internal brown rot disease caused by Neoscytalidium dimidiatum)

4.	https://www.ncbi.nlm.nih.gov/pubmed/24850881 (Neoscytalidium dimidiatum was isolated from a case of eosinophilic fungal rhinosinusitis)

There are actually a lot of papers related to Neoscytalidium dimidiatum on the UOFT library online database. You may take a look at it and hopefully find more information about your fungus. Good luck!

Zikynsk (talk) 22:01, 28 October 2016 (UTC)

Comments by Lipei12
Hi, ADSky

Nice coverage of information on the fungus. Here are some suggestions to help you elaborate your article. First, this may be a minor suggestion, but for organization's sake, you can combine the taxonomy section and the taxonomic difficulty section. It is fine to separate into two sections, but the 2 sections have similar topic, and the taxonomy section is quite short.

Second, you have only mentioned the forms of asexual reproduction. Are there any sexual reproduction? If not, it may be also worth it to mention that it doesn't have sexual reproduction.

Third, you mentioned the fungus as mainly a plant pathogen, but you've only mentioned its pathogenicity in human. You can expand on the fungus's pathogenicity on plants. What species of plants it affects? How and what it does to the plants? Here are some papers that I found on pubmed and web of science relating its effect on plants:

Run Hua Yi. Qiao ling lin. Jun Jie mo. Feng Fa Wu. Jing Chen. 2015. Fruit internal brown rot caused by Neoscytalidium dimidiatum on pitahaya in Guangdong province, China.

Masratul Hawa Mohd. Baharuddin Salleh. Latiffah Zakaria. 2013. Identification and Molecular Characterizations of Neoscytalidium dimidiatum Causing Stem Canker of Red‐fleshed Dragon Fruit ( Hylocereus polyrhizus) in Malaysia.

Rolshausen, P. E. Akgul, D. S. Perez, R. Eskalen, A. Gispert, C. 2013. First Report of Wood Canker Caused by Neoscytalidium dimidiatum on Grapevine in California.

Lastly, you may also expand on some treatments to the fungal infection. Here is a paper I found: Ruíz-Cendoya M. Madrid H. Pastor J. Guarro J. 2010. Evaluation of antifungal therapy in a neutropenic murine model of Neoscytalidium dimidiatum infection.

Overall, your article was detailed and organized. I look forward to your finished article. Well done.

Lipei12 (talk) 22:45, 1 November 2016 (UTC)