User talk:Amaher

Need Some Help
There's an article about a phenomenon where repeat withdrawals from GABAergic drugs paradoxically produces worse and worse withdrawals. The article is, "Kindling (sedative–hypnotic withdrawal)." I am not familiar with how to propose an article be deleted, etc., so I was looking for help as this article, I believe, is misleading thousands of users of GABAergics such as alcohol, benzodiazepines, and gabapentinoids. You can find my complains in the talk page of the article under the header "Original Research." You can look there now, or you can read a brief overview of the problems. Perhaps most important of all, I can't find any scientific articles about kindling, and the cited studies are on random topics like alcohol withdrawal in adolescents, which I assume were all cherrypicked from, using original research to create the article. Most glaringly, the entire introductory paragraphs have ZERO citations despite being the place in the article with the strongest statements about kindling. Also, there isn't a single citation to a study with a title that has "kindling" in its name. If this were a true phenomenon, with how common alcohol, benzodiazepines, and gabapentinoids are, I'd expect there to be multiple reviews on the topic, plenty of double-blind, placebo-controlled trials, and at least one meta-analysis or systematic review. Damn, this article also includes the buzzword sensitization right next to kindling. Please, pick a section and read it, looking at the ridiculous sources used. For example, under the "Pathophysiology -Benzodiazepine" section, you should notice it's mainly talking about how GABA and glutamate are changed in people with benzodiazepine physical dependence. The icing on the cake is the claimed source: "Neuroadaptive processes in GABAergic and glutamatergic systems in benzodiazepine dependence." That's right. It's just a paper about the main excitatory and inhibitory neurotransmitters. If parts of this article can remain, I propose shifting some of these findings to the appropriate topic e.g. seeing if that claimed source and explanation of physical dependence might fit somewhere in the benzodiazepine page. If you can find an actual source claiming kindling is real, you can also add in the credible source and remove all the ones unrelated to kindling.

ArbCom elections are now open!
MediaWiki message delivery (talk) 16:35, 23 November 2015 (UTC)