User talk:Batcheld/sandbox

Comments
Hi, I want to let you know that I think you write really well! I'm glad that your article sounds impartial, and that you state facts instead of sprinkling your own opinion. I just have a few things that I was able to pick out:


 * C. elegan = C. elegans (intro)
 * Localization: maybe remove capital letters from nucleus, cytosol and Mitochondrial? (mid-sentence) and other areas mid-sentence
 * Quick error: "In mammals cellualr Cu levels" *Cellular
 * perhaps link to the 26S proteasome article where it is mentioned?
 * could you explain what "auto-ubiquitination" is? Or maybe re-write it in a way that it becomes understandable without a biology background.
 * When you mention "knockouts," I think most scientists with a background in biology will understand, but most readers will not. Perhaps explain what it is, ie. a biologically engineered organism that didn't express CCS (would have to mention which organism as well).
 * Perhaps also link to the article of upregulation (or another term for upregulation that is less technical), and the other proteins listed.
 * In this phrase: Moreover, SOD1 mutants that have altered interactions with CCS can display misfolding and aggregation" - I'm wondering if this sentence is necessary to include. Technically, any protein that has non-ideal or altered interactions with their binding partner can be misfolded or aggregated. I'm not sure if this is knowledge is specific to this enzyme in particular.

Good luck!

Harris.qureshi (talk) 02:02, 11 March 2015 (UTC)