User talk:CRH16/Coronary vasospasm

Peer Editing
Lead Section:
 * I like this section the most of any on the page. I think it’s a good, comprehensive summary of coronary vasospasm. The only thing I would suggest would be to delete the last sentence. Otherwise, I think the language is appropriate, and it nicely summarizes what is to come in the rest of the article.

Article:
 * I think the organization is appropriate.
 * For the pathophysiology, I think you could elaborate on what “vasoconstrictor stimuli” are by providing some examples. I see they are mentioned later on, but I think it would be helpful to readers to mention some examples in this section. Vasospasm is never defined anywhere, as well, and I think it would be helpful to explain what is meant by vasospasm. I think the page could also benefit from expanding on the pathogenesis and elaborating on how endothelial dysfunction, chronic inflammation, oxidative stress, and smooth muscle hypercontractility contribute to coronary arteries spasming. Source 1 provides greater insight into the pathophysiology that could be expanded upon.
 * For risk factors, the writing gets a little jumbled in the last three sentences. I think it might be hard to follow what triggers the sympathetic nervous system for readers without a medical background. I would suggest making it more clear earlier on in the section what the certain risk factors are and follow by how they work by increasing sympathetic activity.
 * For the signs and symptoms, I would similarly suggest moving the associated signs and symptoms to the beginning of the section (ex. signs and symptoms include…) and then follow on how these may interact and present together.
 * EKG findings I think is written appropriately for this article. It is easy to understand, and I wouldn’t worry about writing this section for non-medical personnel.

References:
 * Every statement seems to be associated with a supporting reference, and the references all seem appropriate and up to date.

Suggestions:
 * I think the page could really benefit from sections on diagnosis, treatment, and prognosis (including complications). In response to the authors’ questions, I don’t think there is too much medical jargon and I think the page could dive even deeper into the pathophysiology, risk factors, and signs and symptoms.
 * I think this article is on its way to becoming a useful resource for patients and a nice, brief review for colleagues. The language is appropriate with limited use of medical jargon except where necessary. I think by adding a few sections on the diagnosis, treatment, and prognosis, it would be a very complete summary of coronary vasospasm.
 * A couple useful sources are here:
 * This source seems to be a good review of the symptoms, diagnosis, and treatment of vasospastic angina: Beijk, M. A., et al. "Myocardial infarction with non-obstructive coronary arteries: a focus on vasospastic angina." Netherlands Heart Journal 27.5 (2019): 237-245.
 * This seems to be a great resource and summation of vasospastic angina: Picard, Fabien, et al. "Vasospastic angina: A literature review of current evidence." Archives of cardiovascular diseases 112.1 (2019): 44-55.

Fredtg11 (talk) 22:14, 19 November 2020 (UTC)fredtg11