User talk:Colettedepardieu/sandbox

Löffler's syndrome or Loeffler's syndrome is a disease in which eosinophils, a variety of white blood cells accumulate in the lungs in response to a parasitic infection. The parasite can be Strongyloides Stercoralis or Dirofilaria immitis. The symptoms of Loeffler’s syndrome include those of a parasitic infection such as irritable bowel syndrome, abdominal pain and cramping, skin rashes and fatigue. The Loeffler’s syndrome itself will cause breathlessness, coughing as well as a fever. It was first described in 1932 by Wilhelm Löffler[1] in cases of eosinophilic pneumonia caused by the parasites Ascaris lumbricoides,[2] Strongyloides stercoralis and the hookworms Ancylostoma duodenale and Necator americanus. The most well known case of Loeffler’s syndrome was in a young boy from Louisiana. He arrived at the hospital with a reported high fever after three days, as well as having rapid breathing. ”He was hospitalized and treated with supplemental oxygen, intravenous methylprednisolone, and nebulized albuterol.” (Loeffler syndrome on a Louisiana pig farm) The boys symptoms quickly subsided and upon further investigation it was discovered that the boy worked caring for pigs. A test was then performed on the pigs fecal matter and surrounding soil and was found to determine to contain the parasite that had cause the boys ailment. Although Löffler only described eosinophilic pneumonia in the context of infection, many authors give the term "Löffler's syndrome" to any form of acute onset pulmonary eosinophilia no matter what the underlying cause. If the cause is unknown, it is specified and called "simple pulmonary eosinophilia". Cardiac damage caused by the damaging effects of eosinophil granule proteins (ex. major basic protein) is known as Loeffler endocarditis and can be caused by idiopathic eosinophilia or eosinophilia in response to parasitic infection.[citation needed]

(Elise Bejvan Nicole Lipase (talk) 21:36, 19 November 2018 (UTC))