User talk:Drshimberbr/NS-NV

NS-NV is Non Systemic Neoplastic Neurogenic Vasculopathy whith ulceration and painfull joins and developing Autoimmune disorder.There are some risk factures about this condition like Liver failure,Renal failure,Palmonary embolism,Stroke,gangrene.

Causes
The causes are not known well,but the most potencial causes are as below
 * neoplasia
 * HIV+ patients
 * Lymphomas
 * Genetic
 * VIRAL INFECTION

Symptoms

 * Joint swelling
 * fever
 * Ulceation around affected area
 * Redness/dizzness (rare)
 * rest pain/short walking distance

diagnosis
Diagnosis may take much time during treatment of other kind of suspected vasculitis as drug resistance effect.HLA B5/51 of this patients are usualy positive.Liver failure test maybe shows elevation of transamines which shows liver may be congasted (liver biopsy needed).Symptoms will not reduce during terapy with Prednisone,MTX,and other immunesupresants. ANCA may present in some patients.

Treatment
Because of developing process of disease,and not responce to drugs amputation of affected limb is recomended in some cases.Remaining of affected limb having some serious problems ,such as liver failure and death.