User talk:Firefly1009

Lead chromate
I agree that it makes sense that PbCrO4 might be carcinogenic and bad for health in general. But when making medical claims, secondary sources are usually required. Reviews in strong journals.

As a practical matter, lead chromate is very insoluble ... A related case is barium sulfate, which is probably isostructural with PbCrO4. Barium salts are highly toxic, but BaSO4 is safe because it is insoluble. It is so safe that medical doctors use it to image the stomach. --Smokefoot (talk) 17:36, 22 October 2023 (UTC)


 * Thanks for the revert + the link to WP:MEDRS! Those sources seemed to be fairly authoritative in stating that insoluble Cr(VI) compounds are more carcinogenic, but I'm definitely missing a review of some sort. Will update if/when I find a good one.
 * Based on what I can tell (which is mostly based on original research from a professor), the insoluble Cr(VI) compounds enter cells via phagocytosis and participate in a series of reduction reactions that generate superoxide, hydrogen peroxide, and hydroxyl radicals. Not sure if I have a great source on that, but it's at least worth finding one to correct the existing paragraph in lead(II) chromate :) Firefly1009 (talk) 17:55, 22 October 2023 (UTC)