User talk:Hammernmill/sandbox

I am having posting an addition to 'segmented filamentous bacteria', see below. It is not posting properly to the Wiki page and I do not know why. Help would be appreciated.

Research on maternal immune activation in mice has demonstrated typical social and repetitive behaviors in offspring when segmented filamentous bacteria were absent from the guts of the mothers. However, if the guts of female mice contained segmented filamentous bacteria, the offspring would show atypical social and repetitive behaviors. These atypical behaviors were linked to changes in the dysgranular zone of the primary somatosensory cortex (S1DZ). [1][2] The research further found that optogenetically engineered mice could have these abnormalities activated or inhibited in response to various wavelengths of light. A separate element of this research determined the S1DZ neurons project into a specific region of the mouse cortex, the temporal association area (TeA), in addition to the striatum. [3] It is suggested that even if these aspects of mouse physiology are not linkable to autism in humans, it still suggests the complexity of the interactions between gut bacteria, the maternal immune system, and development of fetal brain structures and the subsequent consequences in terms of offspring behaviors.[4] Hammernmill (talk) 22:22, 4 October 2017 (UTC) Jump up ^ Powell, C. M. (2017). “Mum’s bacteria linked to baby’s behavior” Nature. Vol 549: 466-467. doi:28 September 2017 Jump up ^ Kim, S.; Kim, H.; Yim, Y. S.; Ha, S.; Koji, A.; Tan, T. G.; Longman, R. S.; Honda, K.; Littman, D. R.; Choi, G. B.; Huh, J. R. (September 2017). “Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring”. Nature. Vol 549: 528-532. doi:10.1038/nature23910 Jump up ^ Yim, Y. S.; Park, A.; Berrios, J.; Lafourcade, M>; Pascual, L. M.; Soares, N.; Kim, J. Y.; Kim, S.; Kim, H.; Waisman, A.; Littman, D. R.; Wickersham, I. R.; Harnett, M. T.; Huh, J. R.; Choi, G. B. (September 2017). “Reversing behavioral abnormalities in mice exposed to maternal inflammation”. Nature. Vol 549: 482-487. doi:10.1038/nature23909 Jump up ^ Powell, C. M. (2017). “Mum’s bacteria linked to baby’s behavior” Nature. Vol 549: 466-467. doi:28 September 2017

Hammernmill (talk) 22:54, 4 October 2017 (UTC)