User talk:Hempelmann

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History of malaria
Hi there, thanks for your contributions. This history section is large enough to be split off into its own article now. I've started the process for you. Please feel free to continue to expand this! Tim Vickers (talk) 18:33, 28 April 2008 (UTC) Can you add more pictures (like mosquitoes in amber)?


 * OK, done. Tim Vickers (talk) 16:56, 4 May 2008 (UTC)

Thanks, looks great (Ernst Hempelmann)


 * I notice Wikipedia doesn't have an article on hemozoin. A bit of an omission! Tim Vickers (talk) 04:04, 5 May 2008 (UTC)

Started an articel on hemozoin, the article needs references and editing, Ernst Hempelmann 12 May 2008

Thank you for uploading Image:Birefringent P.falciparum Pigment.jpg. However, it currently is missing information on its copyright status. Wikipedia takes copyright very seriously. It may be deleted soon, unless we can determine the license and the source of the image. If you know this information, then you can add a copyright tag to the image description page.

If you have any questions, please feel free to ask them at the media copyright questions page. Thanks again for your cooperation. Sdrtirs (talk) 09:10, 7 June 2008 (UTC)

There are no copyrights problems (Public domain), the pigture is my own, can you please send the picture to Hemozoin. Ernst Hempelmann


 * Hi there, I've added this image to the article. If you want to release this image to the public domain just copy the text "" (without the quotes) from this page and add it to this page. All the best Tim Vickers (talk) 16:16, 9 June 2008 (UTC)

Done, EH
 * That should be fine. Thanks for the image, and the excellent work you are doing on History of Malaria! Tim Vickers (talk) 21:10, 9 June 2008 (UTC)

Hi Tim,  thanks for sending the image, the History of Malaria article has the structure of Chloroquine but not Artemisinin, could you add the structure of Artemisinin? Ernst 12.6.2008


 * OK, done. Tim Vickers (talk) 15:29, 12 June 2008 (UTC)

Fine, the next (and last) structure should be Quinine, could you add the structure of Quinine? EH 13.6.2008


 * Sure, I've added this to the article. Tim Vickers (talk) 16:02, 13 June 2008 (UTC)

Hi Tim,

the historian Herodotus  (484 – 425 BC) wrote that the builders of the Egyptian pyramids were given large amount of garlic, to protect them against Malaria. Garlic formed part of the diet of the Israelites in Egypt (Numbers 11:5) and of the labourers employed by Khufu  in constructing the pyramid. But there is no scientific evidence that eating garlic will make a person repellent to mosquitoes.

A second point: Tobacco-smokers believed smoking was healthy, though they did not understand that keeping away the annoying mosquitos was beneficial for its own sake. Do you have any figures or references to support this two points? EH 14.6.2008


 * I'll have a look, but I'm better at the more up-to-date stuff! Tim Vickers (talk) 15:06, 15 June 2008 (UTC)

Hi Tim According to recent references garlic acts as a mosquito repelent as well as a protease inhibitor.

Another point: the complete genomic sequences of Plasmodium falciparum and that of the main mosquito vector Anopheles gambiae are available to researchers worldwide since 2002. These complete genomic sequence data will provide the foundation for nearly all malaria research in the next decades.

Kooij TW, Janse CJ, Waters AP Plasmodium post-genomics: better the bug you know? Nat Rev Microbiol. 2006 May;4(5):344-357.

PMID: 16582929

Can you add some up-to-date informations on genomics as a last point of the malaria history? EH 16.6.2008

Hi Tim, thanks for the up-to-date informations, the last picture which is still missing, is a picture of Ronald Ross, can you add such a picture? EH 24.6.2008

Hi Tim, thanks for the Ross picture. Would it be possible to add as external link the most relevant website for the sequencing of the three genomes of the malaria parasite Plasmodium falciparum, its vector Anopheles gambiae, and the human genome? EH 28.6.2008

Hi Tim, I tried to do some editing 7.July (19th century) and most of the article just disappeared to references, I don't know why, can you please help to move the text back and restore the 19th century part? Many thanks, EH 7.7.2008


 * That happens when there is an unclosed ref tag, ie if you have following it. The software then treats everything after the first tag as references. I've fixed that problem. Was it you who deleted that stuff about the Italians? Or would you like to revert to this version? Tim Vickers (talk) 21:42, 7 July 2008 (UTC)

Many thanks, the contributions of the Italians should be included, I will do it later, EH 8.July 2008

Hemozoin
Hi Tim, a historical picture has been send by email for the hemozoin article: Frerichs FT (1858) Pathologisch-anatomischer Atlas zur Klinik der Leberkrankheiten Band I: Klinik der Leberkrankheiten, Kapitel VIII Die Pigmentleber. Melanämische Leber. Veränderungen der Leber bei Intermittens. 325–368, F. Vieweg und Sohn, Braunschweig EH 19.7.2008

Hi Tim, a 3D image of Chloroquine has been send for the hemozoin article, Chloroquine is an inhibitor of hemozoin biocrystallization and one of the best antimicrobials ever developed EH  26.7.2008

Zymography
Hi Tim, the imprint image has been send to Zymography the name of the file should be Plasmodium knowlesi hemoglobinase imprint (not P.falciparum) please add the reference: Hempelmann, E., Putfarken, B., Rangachari, K., Wilson, R.J.M. (1986) Immunoprecipitation of malarial acid endopeptidase Parasitology 92, 305-312 PMID: 3520446 to the image

thanks, EH 6.Aug 2008


 * Sorry, I'm confused, which reference is the correct one? I have Hempelmann, E., Wilson, R.J.M. (1980) "Endopeptidases from Plasmodium knowlesi", Parasitology 80, 323-330 PMID 6768047 in the image at present, is it from the work described in that paper, or from PMID 3520446? I'll rename the file once the copyright release has been processed. Tim Vickers (talk) 16:07, 6 August 2008 (UTC)

Hi Tim, the imprint technique has been used in both papers, the 1980 paper (PMID 6768047) is a short version (but has all techniques), the 1986 paper (PMID 3520446) has much more details and it may be better to use the second reference.

EH 6.Aug. 2008

Malaria culture
Did you send me some more images? I checked my inbox and archives but I'm not sure which I've uploaded. Are there some missing? Tim Vickers (talk) 14:49, 7 October 2008 (UTC)
 * Three images were send by email but not uploaded yet (three dimensional images of artemisinin, quinine, and chloroquine) for the history of malaria article; if the images are lost I can send them again EH 7. Oct 2008
 * Sorry about that, they ended up in my junk mail folder somehow. I'll upload them now. Tim Vickers (talk) 14:59, 7 October 2008 (UTC)
 * Probably my "delete BMP attachments" filter, I've been getting a lot of image spam recently! Anyway, see Image:Quinine 3-D.png, Image:Chloroquine 3D.png and Image:Artemisinin 3D.png. Tim Vickers (talk) 15:10, 7 October 2008 (UTC)

The three images are now uploaded, EH 7 Oct 2008
 * Another image has been send: the protocoll of the first malaria treatment with methylene blue, EH 8 Oct 2008
 * Image:Gutmann & Ehrlich.png. Tim Vickers (talk) 17:43, 8 October 2008 (UTC)

Dear Tim,    the next image for the history of malaria article is taken from Laveran's first communication: Laveran CLA. Note sur un nouveau parasite trouvé dans le sang de plusieurs malades atteints de fièvre palustres. Bull Acad Med 1880; 9: 1235-1236. please upload the image and I will do the rest, EH 9 Oct 2008
 * Image:Laveran malaria drawings.png. Tim Vickers (talk) 17:08, 9 October 2008 (UTC)


 * Image:Antigen capture assay.png. I assumed this was your own work? Tim Vickers (talk) 16:55, 27 October 2008 (UTC)


 * Image:Trager & Jensen.jpg. Tim Vickers (talk) 02:55, 10 November 2008 (UTC)


 * Image:P.falciparum schizont.jpg. Tim Vickers (talk) 17:54, 10 November 2008 (UTC)

The description should be: Giemsa-stained Plasmodium falciparum showing the mature schizont stage of the erythrocytic cycle. The hemozoin containing residual body is visible as a brown body. EH 11 Nov 2008


 * Image:Silver-stained SDS-PAGE gels before and after storage.jpg. Tim Vickers (talk) 16:42, 14 November 2008 (UTC)

Thanks for sending the image, please change the file discription, not Unbenannt but "Giemsa publication" EH 17 November 2008


 * Sorry, now at Image:Giemsa publication (1904).png. Tim Vickers (talk) 17:25, 19 November 2008 (UTC)


 * David's image at Image:Hemozoin crystals.jpg. Tim Vickers (talk) 16:09, 21 November 2008 (UTC)


 * Image at File:Artemisia annua.jpg. Sorry that took so long Tim Vickers (talk) 17:54, 20 December 2008 (UTC)


 * Image at File:Heme Halofantrine complex.png. I converted this to a PNG. Tim Vickers (talk) 23:04, 11 January 2009 (UTC)

A new image "Chloroquine and halofantrine interfere with the biocrystallization of heme" has been send by mail Ernst Hempelmann 20 Feb 2009


 * See File:Drug-heme interaction.png. Tim Vickers (talk) 20:48, 20 February 2009 (UTC)

History of malaria as a GA?
Hi there. I'm very impressed by how this article has progressed, would you be interested in nominating it for review as a candidate Good article? Tim Vickers (talk) 17:27, 4 November 2008 (UTC)


 * Hi Tim, thanks for the suggestion. Please nominate the article for review. I also contributed to another article SDS PAGE, may be a better candidate.

EH 5. Nov 2008


 * I've already got a candidate up, I don't like to flood the system. If you wanted to try this, the instructions are at Good article nominations, and are pretty straightforward. Tim Vickers (talk) 17:19, 5 November 2008 (UTC)

Genetic resistance to malaria
New Plasmodium image. Tim Vickers (talk) 17:29, 18 December 2009 (UTC)


 * There are also some useful images at Commons already, but this one looks the best to me! Tim Vickers (talk) 17:31, 18 December 2009 (UTC)

two images (malaria related red blood cell abnormalities) have been send by email Hempelmann (talk) 17:11, 16 September 2010 (UTC)

Hemozoin
An image of pure hemozoin has been send by email. Many hemozoin purification techniques have been published but without any images. Hempelmann (talk) 06:07, 29 April 2010 (UTC)

Romanowsky stain
A new image has been send by email : Portrait of Ernst Malachowski, the father of the polychromatic staining techique, the so called Romanowsky stain Hempelmann (talk) 20:37, 15 February 2010 (UTC)

Malaria antigen detection tests
Started to send images for the article, first image is a counter-immunelectrophoresis of Malaria-antigens/antibodies followed by enzyme staining Hempelmann (talk) 16:01, 3 February 2010 (UTC)
 * You might want to expand the description a bit, I didn't know this was an enzyme stain. Tim Vickers (talk) 17:08, 3 February 2010 (UTC)

Talk:Genetic resistance to malaria/GA1
Hi, I have left some comments regarding your GA nomination at Talk:Genetic resistance to malaria/GA1. Basically, I was overwhelmed with the format of the article. Has it been to WP:peer review? The article appears to have much excellent information, but it needs formatting and copy editing. I have asked for a second opinion of my review, as I would like you to get helpful feedback. Warmest regards, Xtzou ( Talk ) 16:35, 3 May 2010 (UTC)
 * Any helpful feedback is most welcome, if you can improve the article please do Hempelmann (talk) 06:41, 5 May 2010 (UTC)

GA reassessment: History of malaria
History of malaria, an article that you or your project may be interested in, has been nominated for an individual good article reassessment. If you are interested in the discussion, please participate by adding your comments to the reassessment page. If concerns are not addressed during the review period, the good article status may be removed from the article. Sbalfour (talk) 02:43, 16 March 2014 (UTC)

For your wonderful help editing History of malaria, I award you this delicious Wikicookie!
This is the kind of cooperation that realy gets articles to shine, and I have noted your present and past contributions to the article, so here is your just dessert, eat and enjoy!



Sbalfour (talk) 23:41, 23 March 2014 (UTC)

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