User talk:INNOCENT BESTMAN

BESTINNO

Who is Bestinno
Innocent Bestman is a medical laboratory personnel known locally for free Medical outreaches. A christian entertainer. And lover of professional wrestling (WWE). Bestman Innocent is nicknamed Bestinno of LAFEEDERS ( a group of friends with the vision of self development, aka HUSTLE). Favourite WWE chant: FEED ME MORE! Hobbies: wrestling, Med outreaches and research INNOCENT BESTMAN (talk) 06:41, 22 November 2020 (UTC)

RENAL THRESHOLD
Renal Clearance and Renal Threshold Renal Clearance Renal Clearance value indicates the degree to which a substance is removed from the blood by excretion in the urine. Clearance is usually defined as the blood volume that contains the quantity of a substance excreted in the urine per minute. About 120 ml of glomerular filtrate is produced per minute. The rate at which the glomerular filtrate is formed is known as the glomerular filtration rate (GFR). Creatinine is a substance present in the filtrate, which is not reabsorbed (however, this is some tubular secretion of creatinine). Therefore the clearance of creatinine from the plasma is 120 ml per minute. Hence creatinine clearance is used clinically to give an approximate indication of glomerular filtrate rate and, therefore, as a test of kidney function. When the filtration rate falls, the concentration of creatinine in the plasma rises. The creatinine clearance test express the volume of blood containing the amount of creatinine excreted by the kidney in one minute. The creatinine clearance (Ccr) is calculated by collecting a 24 hr urine specimen, and a blood sample as well within the urine collection time. Creatinine is then determined in both urine and serum, and the creatinine clearance calculated in milliliters per minute  (ml / minute) Ccr ml / minute =  U x V                                   S  Where  U= Urine Creatinine Concentration in mol/l V= Volume of urine in ml per 24 hrs S= Serum Creatinine Concentration in mol/l Normal Range: The normal Ccr value usually ranges between 110 – 140 ml / minute. Renal Threshold The renal threshold of a substance refers to the highest concentration of a substance, which is present in the blood before it is found in the urine. A substance such as glucose is a high threshold substance, because it is completely absorbed from the glomerular filtrate and is only found in the urine, when the blood glucose level is markedly raised. Urea and creatinine, however, are always present in the urine independent of the blood level because very little, if any, of these substance is reabsorbed. INNOCENT BESTMAN (talk) 06:50, 22 November 2020 (UTC)