User talk:Javelinhands

"There was a paragraph claiming 1. That PCP is a hallucinogen, which is incorrect and 2. That LSD produced "intense" and "long lasting" psychotic symptoms in users, which there is no evidence for and which likely originated with the myth that LSD is stored in the spine after use. Any hallucinogenic drug is contraindicated for individuals with psychotic disorders and who are at risk for developing them, but the drug class of hallucinogen does not properly fit the description for psychotomimetic."

1. PCP IS a hallucinogen. Hallucinogens are: psychedelics (LSD, psilocin), dissociatives (PCP, ketamine, DCK), and deliriants (diphenhydraine, datura, etc.) 2. What the fu--. LSD is one of the longer lasting psychedelics. This is because the 5-HT2A receptor forms a "cap" over the LSD molecule, trapping it in a bound state for a longer amount of time than other hallucinogens. That you speculated it was related to that random myth is unfounded. 3. Yes it does because they overlap. Hallucinogen = one of the three categories I said. This is also on Wikipedia. Psychotomimetic is psychosis-inducing. They're not the same, but that doesn't mean that they can't overlap significantly...

I concede that dissociatives fall under the hallucinogen umbrella - I was in error when I wrote that.

The previous version lumped PCP and LSD together, which is really what I objected to. It said “LSD and PCP can produce intense psychotomimetic effects that may last for days or cause permanent brain alterations.” I maintain that this sentence is imprecise, and that “permanent brain alterations” is scaremongering. I know the mechanism of LSD and was not disputing that it’s a long trip.

Nevertheless I think you’re right and that all classes of hallucinogens are technically psychotomimetic. Though the features, mechanisms, and risks are different and I don’t think that should be glossed over. Javelinhands (talk) 17:22, 5 May 2022 (UTC)