User talk:Jwanderson

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Glycation
Hey Jwanderson, thanks for your message. I'm hardly into glycochemistry; my dealings have been more with glycosylation, and I'm eagerly awaiting the results of some experiments. Still, I'm pleased to see your rigorous additions about a subject that is not easily covered on a general encyclopedia. Kudos.

Are you making a userpage for yourself? Even a quirky quote or a random rant is sufficient.

I have found contibuting to Wikipedia a good learning curve. English is not my first language, and writing lay-oriented scientifically grounded text has probably helped my writing skills. In addition, the typo team sometimes has to clean up after me... JFW | T@lk  20:01, 25 Jan 2005 (UTC)

PS: Could you write something about advanced glycation endproducts? I linked to this from G6PD, but had no material to write more on AGEs.

glycosylation vs glycation Welcome to wikipedia. Terminology question. I saw both articles and a distinction being made between the two. I understand the point of the distinction (enzymatic vs non-enzymatic) but have never heard it before. Specifically, these articles imply that we should be referring to glycosylated hemoglobin as glycated hemoglobin, a distinction I've never noticed in the context of diabetes research and medical care. I have been reading the diabetes literature for nearly 30 years and glycosylated hemoglobin was the topic of my first research publication in 1978. While I have heard the term "glycated Hb" in recent years, it is still a minority usage. A google search says glycosylated hemoglobin is preferred over glycated hemoglobin by 3 to 1 (I actually expected a greater disparity). Is it accurate to say that some basic chemists have tried to introduce this distinction in the terminology but it is largely ignored by clinical scientists and physicians? Your reference to "age-related type 2 diabetes" tells me you are unfamiliar with diabetes (GHb measurements were pioneered in type 1 pts, and the age comment is inaccurate), but perhaps you know more glycochemistry than I do or usage is changing and I haven't noticed it. I am considering editing the two articles to explain this usage discrepancy to the reader interested in diabetes. Can you give me a reference in which the distinction between enzymatic glycosylation and non-enzymatic glycation is made? alteripse 03:20, 9 Mar 2005 (UTC)