User talk:Kayladanesh/sandbox

Isabel's Peer Review Does the article flow well? Well Organized? The article is well organized into sections that are connected with one another but still provide distant information from the other sections. The introduction provides a clear explanation of what intracellular pH and is helpful in reading the rest of the article. However, I would recommend placing the section “How Intracellular pH is maintained” after the introduction because I feel like that has a bit more connection to the introduction given that you end the introduction with the importance of regulation.

•	Is the level of detail appropriate? Not too much or too little? There are some places where more details can be added, such as the microelectrode section. I would recommend providing more detail about the procedure to measure pH with an electrode. How do they have a predetermined pH? Why is it important to have a predetermined pH? What does the voltage difference specifically tell us about the pH (i.e., is a high voltage difference a low or high pH)?

•	Well organized: is content in the appropriate section and not redundant? The content is well organized into distinct sections and no information is redundant across the sections.

•	Does each section stand alone? Each section can stand alone because no information is placed under the incorrect method. It is clear what each section is discussing.

•	Is it neutral? The article is neutral and does not feel like a persuasive article. Each topic is presented equally and neutrally. I would recommend just being careful when discussing the advantages and disadvantages for each method to ensure that no one method is depicted as the better method.

•	Is everything cited? Everything is cited. However, it seems that a lot of citations include reference number 7. You should try to incorporate more of your references more often so your article is not largely written based on one reference.

•	Are there grammatical errors? I did not find any grammatical errors.

•	What images would be useful? An image that depicts the process of placing an electrode into the cell cytosol would be helpful because right now it is hard to imagine what is being placed into the cell and how that it possible. Also, a reaction that demonstrates how CO2 and HCO3- are able to maintain pH would be helpful and could contribute to the scientific accuracy of the article. I would recommend using these reactions to briefly explain how the buffer maintains pH.

•	All images are explained clearly No images are provided yet, but I would just advice to clearly explain any reactions and describe procedural pictures.

•	Is it clear? The article is well written and manageable to understand. No irrelevant information is provided that could prevent reader from understanding the concept.

•	Is there irrelevant information, or relevant info missing? I would recommend talking more about how a voltage difference detected by the electrode can tell us the pH. Is a high voltage indicative of a low or high pH? How are they related as measurements?

•	Scientific inaccuracy The content of the article is scientifically accurate and clearly described.