User talk:Luka.m12

Your points look great so far, just found a few things that might be good to add to your article. A good point to mention is the confusion between E.crescens and E. parva. E. crescens and E. parva are distinct species. E. crescens isolates are placed into two groups that correlate with their continents of origin. Since there is much confusion between the two, also something good to mention would be procedures that are used to make a distinction between them. Diagnosis has relied on histological examination of biopsies for large round or oval, thick walled adiaspores using PAS or other stains. In addition, the use of molecular techniques are a valuable approach for improving the detection and diagnosis in humans. Another point worth noting is that since it is extremely rare in humans it has been reported that it occurs particularly in patients with AIDS. Last comment that I have is that I noticed you talk about how they enter the body but did not go into much detail about how it develops once inside the body. Once inhalation of E. parva occurs, it expands to become adiaspores, which causes a granulomatous inflammation reaction, leading to pulmonary disease known as adiaspiromyeosis. Sometimes the disease may persist resulting in pneumonia or fatal respiratory failure. Great job overall! Below are the links for this information.

http://sabouraudia.oxfordjournals.org/content/13/1/52.short http://jcm.asm.org/content/36/10/2918

Emmonsia parva var. parva [MB#417794] http://www.cbs.knaw.nl/Collections/BioloMICS.aspx?Link=T&TableKey=14682616000000063&Rec=24780&Fields=All