User talk:Marissa3/sandbox

Adding to an Article
I am adding to the Article Hantavirus (https://en.wikipedia.org/wiki/Hantavirus) and the sections Vaccines and Treatment. I wanted to add to this article because over the summer at Mountain Lake I worked with some of the carriers of this virus and I wanted to learn more about the disease. I want to add information about immunotherapy and more information about vaccines. IN the vaccine section I added the last two sentences and in the Treatment section I added the last four sentences to the first paragraph.

Vaccine

As of 2016 there is no commercially available vaccine that is effective for hantavirus.[29] A vaccine known as Hantavax has been under study since 1990. As of 2016, the development is in clinical phase 3 trial stage.[30] This inactivated vaccine is thought not to be effective against European hantaviruses like the Puumala (PUUV) virus.[31] There is no FDA approved vaccine available and a killed-virus vaccine is not being pursued because of the dangers associated with mass production under high containment as well as the unresolved questions about the efficiency of the vaccine. However, a number of labs have been working towards a vaccine that would deliver viral antigens by either DNA vectors or as recombinant proteins.[32]

Treatment

There is no known antiviral treatment, but natural recovery from the virus is possible with supportive treatment. Patients with suspected hantavirus are usually admitted to the hospital and given oxygen and mechanical ventilation support to help them breathe during the acute pulmonary stage.[15] Immunotherapy, or the treatment of diseases with substances that stimulate the immune response, for this virus has shown that administration of human neutralizing antibodies during these acute phases of Hantavirus might prove effective for treatment. A strong neutralizing antibody could effectively reduce the presence of the virus as well as promote recovery. However, there are no published reports of controlled clinical trials except for studies done on mice, hamsters, and rats. Those trials have been successful in protecting those animals from the virus.[32]

32. Jonsson, Colleen B.; Hooper, Jay; Mertz, Gregory (2016-10-12). "Treatment of hantavirus pulmonary syndrome". Antiviral research. 78 (1): 162–169. doi:10.1016/j.antiviral.2007.10.012. ISSN 0166-3542.

Marissa3 (talk) 01:07, 12 October 2016 (UTC)