User talk:Nsr009/Pulmonary fibrosis

Pulmonary fibrosis involves gradual exchange of normal lung parenchyma with fibrotic tissue. The replacement of normal lung with scar tissue causes irreversible decrease in oxygen diffusion capacity, and the resulting stiffness or decreased compliance makes pulmonary fibrosis a restrictive lung disease.[15] Pulmonary fibrosis is perpetuated by aberrant wound healing, rather than chronic inflammation.[16] It is the main cause of restrictive lung disease that is intrinsic to the lung parenchyma. In contrast, quadriplegia[17] and kyphosis[18] are examples of causes of restrictive lung disease that do not necessarily involve pulmonary fibrosis.

By looking at molecules implicated in pulmonary fibrosis, we can look at molecules such as P53, a tumor suppression protein implicated in the cell cycle and cell apoptosis.