User talk:Os2hoppy

Welcome!
Hello, Os2hoppy, and welcome to Wikipedia! Thank you for your contributions. I hope you like the place and decide to stay. Here are some pages that you might find helpful: I hope you enjoy editing here and being a Wikipedian! Please sign your messages on talk pages using four tildes ( ~ ); this will automatically insert your username and the date. If you need help, check out Questions, ask me on my talk page, or ask your question on this page and then place  before the question. Again, welcome! --ἀνυπόδητος (talk) 16:17, 6 November 2012 (UTC)
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Vandetanib
Hi! I noticed that you changed the excretion of vandetanib via the faeces from 63% to 44%, however the source (http://www.drugs.com/monograph/vandetanib.html) says 63%, and so I have changed it back. Do you have a different source? If yes, it would be great if you could name it so that we can make sure the article states the correct percentage. (See Verifiability for our policy on sourcing.) Thanks, and happy editing, ἀνυπόδητος (talk) 16:17, 6 November 2012 (UTC)

Hi, I am an Oncology pharmacist that specializes in these medications. Drugs.com is not an accurate resource for sourcing the details of medications - they are more interested in sales than accuracy! The definitive phase I pharmacokinetic study determined that 44% of the drug was eliminated in the feces. That reference is here http://www.ncbi.nlm.nih.gov/pubmed/22206795 as well as the product monograph of the medication http://www1.astrazeneca-us.com/pi/vandetanib.pdf (page 5: Excretion Within a 21-day collection period after a single dose of 14C-vandetanib, approximately 69% was recovered with 44% in feces and 25% in urine. Excretion of the dose was slow and further excretion beyond 21 days would be expected based on the plasma half-life.) Os2hoppy (talk) 01:17, 16 November 2012 (UTC)os2hoppy
 * Thanks for the clarification! I've added the source to the article. Cheers, ἀνυπόδητος (talk) 10:47, 28 November 2012 (UTC)