User talk:Ricardus Cibarius

I would liker to propose a revision of the article, RNAIII, and I would like to show the proposed revision to the author of the article before submitting my proposed revision. My proposed revision follows:

RNAIII is a stable 514 nt regulatory RNA transcribed by the P3 promoter of the Staphylococcus aureus quorum-sensing agr system. It is the major effector of the agr regulon, which controls the expression of many S. aureus genes encoding exoproteins and cell wall-associated proteins plus others encoding regulatory proteins. The RNAIII transcript also encodes the 26 amino acid delta-haemolysin peptide (Hld). RNAIII contains many stem loops, most of which match the Shine-Dalgarno motif involved in translation initiation of the regulated genes. Some of these interactions are inhibitory, others stimulatory; among the former is the regulatory protein Rot. In vitro, RNAIII is expressed post-exponentially, inhibiting translation of the surface proteins, notably protein A, while stimulating that of the exoproteins, many of which are tissue-degrading enzymes or cytolysins. Among the latter is the important virulence factor, α-hemolysin (Hla), whose translation RNAIII activates by preventing the formation of an inhibitory foldback loop in the hla mRNA leader. Ricardus Cibarius (talk) 16:32, 22 November 2020 (UTC)

Your submission at Articles for creation: Accessory gene regulator has been accepted
 Accessory gene regulator, which you submitted to Articles for creation, has been created.

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Thanks again, and happy editing! Gpkp  [ u • t • c ] 06:46, 23 November 2020 (UTC)