User talk:ShaUN miranDA

Niacin

Kekulé, skeletal formula of niacin

Ball and stick model of niacin

Names

Preferred IUPAC name

Pyridine-3-carboxylic acid[1] Other names Nicotinic acid (INN) Bionic Vitamin B3

Identifiers

CAS Number 59-67-6 Yes 3D model (Jmol) Interactive image 3DMet B00073

Beilstein Reference 109591 ChEBI CHEBI:15940 Yes ChEMBL ChEMBL573 Yes ChemSpider 913 Yes DrugBank DB00627 Yes ECHA InfoCard 100.000.401 EC Number 200-441-0

Gmelin Reference 3340

IUPHAR/BPS 1588 KEGG D00049 Yes MeSH Niacin PubChem 938 RTECS number QT0525000 UNII 2679MF687A Yes

InChI[show]

Yes

Yes

SMILES[show]

Properties

Chemical formula C 6NH 5O 2 Molar mass 123.1094 g mol−1 Appearance White, translucent crystals Density 1.473 g cm−3 Melting point 237 °C; 458 °F; 510 K

Solubility in water 18 g L−1 log P 0.219 Acidity (pKa) 2.0,4.85 Isoelectric point 4.75

Refractive index (nD) 1.4936

Dipole moment 0.1271305813 D

Thermochemistry

Std enthalpy of formation (ΔfHo298) −344.9 kJ mol−1

Std enthalpy of combustion (ΔcHo298) −2.73083 MJ mol−1

Pharmacology

ATC code C04AC01 (WHO) C10AD02 (WHO)

Routes of administration Intramuscular, Oral Pharmacokinetics:

Biological half-life 20–45 min

Hazards

EU classification (DSD) Irritant Xi R-phrases R36/37/38 S-phrases S26, S36 NFPA 704

NFPA 704 four-colored diamond

1

1

0 Flash point 193 °C (379 °F; 466 K)

Autoignition temperature 365 °C (689 °F; 638 K)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Yes verify (what is Yes ?) Infobox references

Niacin, also known as vitamin B3 and nicotinic acid, is an organic compound with the formula C 6H 5NO 2 and, depending