User talk:Wjthompson/sandbox

My chosen topic is Non-homologous Isofunctional Enzymes. These are two unrelated enzymes that have evolved seperatly to catalyze the same reaction. I plan to contribute more detailed information about my topic as there is currently only a description of what it is. I plan on creating a history of how they came to be discovered as well as other topics such as relevance and medical importance.

Some sources i plan to reference

From YounJi nam
It is a good summary of your subject, but I don't see much about the evolutionary aspects of your subject. It will look better with that. Plus, I see there are redundancy in your first paragraph, talking about DNA and protein sequences. You can make it concise. One more, it will be wonderful if you put applications of your topic to any evolutionary studies. Please let me know if you want me to elaborate further! — Preceding unsigned comment added by Ynam1 (talk • contribs) 00:16, 17 November 2017 (UTC)

From Ryan Lavoie
First, in the lead, it should be "...enzymes that catalyze the same chemical...", not catalyzeS. There's also an issue with a second period after "...similarity. .As...". I also don't think the last sentence of the first paragraph is entirely necessary, the lead is supposed to be a very brief intro of what the topic is and not go into specifics. That article would also need to be referenced. You could add a section talking about how the NISE's are discovered, in general, if that kind of information is available/relevant. It would also be nice to put your examples of NISE's under an "Examples" subheading. I doubt it's worth it to try and find enough examples to categorize the examples by function or anything like that though. It may be good to add a reason why the enzymes having the same EC number is an issue, that seems like useful info. Relavoie (talk) 00:30, 18 November 2017 (UTC)