User talk:Yayinruan/NAD+ glycohydrolase/Petvyli Peer Review

Peer Review
Hi Yayin,

I think you have contributed well to this article. Initially, there was no section on how this enzyme regulates the immune system so you added a specific section that increases reader's understanding of what this enzyme does. I like your lead sentence as it is clear and straight to the point. You introduced new enzymes CD38 and SARM1 and then explain them in new subsections. However, one thing I would improve on is wording and some grammar. For example, "Cells that are programmed for cell death or apoptosis releases NAD+, and type II CD38 help recycle the extracellular NAD+ released from apoptosis, where both products of NADase, ADP-ribose and nicotinamide, can be used to resynthesize NAD+ via the NAD+ synthesis pathway." I think this can be broken down into two sentences and there is a minor spelling error of NDAse.

Reformatted: Cells that are programmed for cell death (apoptosis) releases NAD+, and type II CD38 help recycle this extracellular NAD+. ADP-ribose and nicotinamide, products of NADase, can be used to resynthesize NAD+ via the NAD+ synthesis pathway."

I would also like some explanation behind how scientists named these enzymes as CD38 and SARM1. Is there a reason you chose these two specific enzymes, are they the two that is mostly regulated by NADase?

Overall, I think you did a well done job. The lead is clear and straight to the point. There was already broad information on what NADase is so it was a good addition to add a specific section. You wrote in a clear structure, spoke in a neutral tone and cited from reliable sources. Good job. Petvyli (talk) 22:32, 5 May 2024 (UTC)Petvy Li