VLB

VLB may refer to:

Science and technology

 * VESA Local Bus, a local bus based on the Intel 80486 CPU
 * Very large board, a large printed circuit board
 * Vincaleukoblastine, or vinblastine, an antitumor alkaloid

Other uses

 * VLB Berlin (Versuch- u. Lehranstalt für Brauerei in Berlin), a brewing school and trade organization in Berlin
 * Volunteer Life Brigade, the forerunners of today Auxiliary Coastguard in the United Kingdom