Valine N-monooxygenase

Valine N-monooxygenase (, CYP79D1, CYP79D2) is an enzyme with systematic name L-valine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction


 * L-valine + 2 O2 + 2 NADPH + 2 H+ $$\rightleftharpoons$$ (E)-2-methylpropanal oxime + 2 NADP+ + CO2 + 3 H2O (overall reaction)
 * (1a) L-valine + O2 + NADPH + H+ $$\rightleftharpoons$$ N-hydroxy-L-valine + NADP+ + H2O
 * (1b) N-hydroxy-L-valine + O2 + NADPH + H+ $$\rightleftharpoons$$ N,N-dihydroxy-L-valine + NADP+ + H2O
 * (1c) N,N-dihydroxy-L-valine $$\rightleftharpoons$$ (E)-2-methylpropanal oxime + CO2 + H2O (spontaneous reaction)

Valine N-monooxygenase is a heme-thiolate protein (P-450).