Vesicular glutamate transporter 3

Vesicular glutamate transporter 3 (VGLUT3) is a protein that in humans is encoded by the SLC17A8 gene.

Function
This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft.

Clinical significance
Mutations in this gene are the cause of autosomal-dominant nonsyndromic deafness type 25 (DFNA25).