WMSB

WMSB may refer to:


 * WMSB (FM), a radio station (88.9 FM) in Byhalia, Mississippi
 * WLRK (FM), a radio station (91.5 FM) in Greenville, Mississippi, which held the call sign WMSB in 2003
 * WKAR-TV a television station in East Lansing, Michigan, which held the call sign WMSB from 1959 to 1972