WPB

WPB may refer to:
 * War Production Board, a US government agency in WWII
 * War Propaganda Bureau of Britain's Foreign Office in WWI
 * Weekly Playboy, Japanese men's magazine
 * Weibel–Palade body, storage granules of endothelial cells
 * West Palm Beach, Florida, United States, a city
 * World Painted Blood, a 2009 album by the thrash metal band Slayer
 * Waste paper basket
 * The hull classification symbol of an Island-class patrol boat of the US Coast Guard
 * Port Bergé Airport, Madagascar
 * World Prison Brief, database of prison systems throughout the world
 * Whizz Pop Bang, a science magazine for children

Political parties

 * Workers Party of Bangladesh
 * Workers' Party of Belgium
 * Workers Party of Britain